Diamondbacks vs. Brewers prediction: Why Milwaukee is favored to win Wednesday's MLB matchup [8/27/2025]

The Milwaukee Brewers will take on the Arizona Diamondbacks in MLB action at American Family Field on Wednesday, starting at 7:40PM ET.

Aaron Ashby (2-1, 2.09 ERA) will start for the Brewers, while the Diamondbacks have opted for Ryne Nelson (6-3, 3.63 ERA).

Based on the latest simulation results, Dimers' proven MLB model predicts the Brewers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Diamondbacks-Brewers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Brewers' chance of winning at 55%, with the Diamondbacks at 45%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Diamondbacks vs. Brewers predictions page.

Brewers vs. Diamondbacks prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's MLB game between the Diamondbacks and Brewers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Brewers a 55% chance of defeating the Diamondbacks.

According to our model, the Diamondbacks (+1.5) have a 63% chance of covering the run line, while the 8.5-run over/under has a 52% chance of going over.

Diamondbacks vs. Brewers odds [8/27/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Diamondbacks	Brewers
Run Line	+1.5 (-170)	-1.5 (+152)
Moneyline	+120	-136
Total	o8.5 (-115)	u8.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Diamondbacks vs. Brewers picks and best bets

Our model's biggest edge in today's Diamondbacks vs. Brewers matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Diamondbacks vs. Brewers game-day updates and essential details

Wednesday's MLB game between the Brewers and Diamondbacks at American Family Field is scheduled to start at 7:40PM ET.

• Who: Arizona Diamondbacks vs. Milwaukee Brewers
• Date: Wednesday, August 27, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: American Family Field

Dimers.com's in-depth preview of Wednesday's Diamondbacks vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Diamondbacks vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Brewers, with a 55% win probability, will likely beat the Diamondbacks on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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