Diamondbacks vs. Rockies Prediction: Arizona Predicted to Win Saturday's MLB Matchup [6/21/2025]

The Colorado Rockies and Arizona dbacks will meet in MLB action at Coors Field on Saturday, starting at 9:10PM ET.

Carson Palmquist (0-4, 7.76 ERA) will be on the bump for the Rockies, up against Merrill Kelly (6-3, 3.41 ERA) for the Diamondbacks.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Diamondbacks-Rockies game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Diamondbacks are more likely to win, while the Rockies have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Diamondbacks vs. Rockies predictions page.

Rockies vs. Diamondbacks Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Saturday's MLB game between the Diamondbacks and Rockies 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Diamondbacks a 61% chance of beating the Rockies.

According to our model, the Diamondbacks (-1.5) have a 51% chance of covering the run line, while the 12.5-run over/under has a 58% chance of staying under.

Diamondbacks vs. Rockies Odds [6/21/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Diamondbacks	Rockies
Run Line	-1.5 (-140)	+1.5 (+122)
Moneyline	-200	+168
Total	o12.5 (-110)	u12.5 (-103)

All odds are correct at the time of publication and are subject to change.

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Diamondbacks vs. Rockies Picks and Best Bets

Our model's biggest edge in today's Diamondbacks vs. Rockies matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Diamondbacks vs. Rockies Game-Day Updates and Essential Details

Saturday's MLB action between the Rockies and Diamondbacks at Coors Field is scheduled to start at 9:10PM ET.

• Who: Arizona Diamondbacks vs. Colorado Rockies
• Date: Saturday, June 21, 2025
• Time: 9:10PM ET/6:10PM PT
• Venue: Coors Field

Dimers.com's full preview of Saturday's Diamondbacks vs. Rockies matchup includes our prediction, picks and the latest betting odds.

Before making any Diamondbacks vs. Rockies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Diamondbacks, with a 61% win probability, will likely beat the Rockies on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Rockies insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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