Amanda Anisimova vs. Iga Swiatek prediction, odds, picks for US Open 2025

Amanda Anisimova and Iga Swiatek will lock horns in the quarterfinals of the US Open 2025 on Wednesday.

Based on the latest simulation results, Dimers' proven tennis model predicts Iga Swiatek as the most likely winner of the match.

"We have simulated the outcome of Wednesday's Anisimova-Swiatek match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Iga Swiatek's chance of winning at 79%, with Amanda Anisimova at 21%."

For a closer look at Wednesday's match, including best bets and picks, visit our interactive Anisimova vs. Swiatek predictions page.

Anisimova vs. Swiatek prediction: Who will win and advance to the semifinals?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's Anisimova-Swiatek women's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Swiatek a 79% chance of winning against Anisimova in the US Open 2025.

Additionally, Swiatek has a 73% chance of winning the first set, while the under 20.5 games has a 54% chance of hitting, according to our model.

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Amanda Anisimova vs. Iga Swiatek odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Anisimova	Swiatek
Moneyline	+330	-455
First Set	+240	-303
Total Games	o20.5 (-110)	u20.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Anisimova vs. Swiatek picks and best bets

Our model's biggest edge in today's Anisimova vs. Swiatek match is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Anisimova vs. Swiatek updates and essential details

The US Open 2025 match between Amanda Anisimova and Iga Swiatek is scheduled to begin on Wednesday at 4:00PM ET.

• Who: Amanda Anisimova vs. Iga Swiatek
• Date: Wednesday, September 3, 2025
• Approx. Time: 4:00PM ET/1:00PM PT
• Tournament: US Open Women's Singles 2025
• Round: Quarterfinals

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's in-depth preview of Wednesday's Anisimova vs. Swiatek match includes our prediction, picks and the latest betting odds.

Before making any Amanda Anisimova vs. Iga Swiatek picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Iga Swiatek, with a 79% win probability, will likely beat Amanda Anisimova at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Anisimova vs. Swiatek insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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