Alexei Popyrin vs. Holger Rune Prediction, Odds, Picks for ATP Canadian Open 2025

Alexei Popyrin will square off with Holger Rune in the round of 16 at the ATP Toronto event on Saturday.

Based on the latest simulations, Dimers' advanced tennis model (see Dimers Pro for full access) predicts Holger Rune as the most likely winner of the match.

For a closer look at Saturday's match, including best bets and picks, visit our interactive Popyrin vs. Rune predictions page.

Popyrin vs. Rune Prediction: Who Will Win and Advance to the Quarterfinals?

Using innovative machine learning and data, we have simulated the outcome of Saturday's Popyrin-Rune men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model gives Rune a 60% chance of defeating Popyrin at the ATP Canadian Open tournament.

Additionally, Rune has a 58% chance of winning the first set, according to our model.

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Alexei Popyrin vs. Holger Rune Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Popyrin	Rune
Moneyline	+175	-227
First Set	+150	-189

All odds are correct at the time of publication and are subject to change.

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Popyrin vs. Rune Picks and Best Bets

Our model's strongest edge in today's Popyrin vs. Rune match is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Popyrin vs. Rune Updates and Essential Details

The ATP Canadian Open match between Alexei Popyrin and Holger Rune is scheduled to commence on Saturday at 7:00PM ET.

• Who: Alexei Popyrin vs. Holger Rune
• Date: Saturday, August 2, 2025
• Approx. Time: 7:00PM ET/4:00PM PT
• Tournament: ATP Toronto, Canada Men's Singles
• Round: Round of 16

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Saturday's Popyrin vs. Rune match includes our prediction, picks and the latest betting odds.

Before making any Alexei Popyrin vs. Holger Rune picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Holger Rune, with a 60% win probability, will likely beat Alexei Popyrin at the ATP Canadian Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Popyrin vs. Rune insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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