49ers vs. Packers Predictions and Odds - Jan 22, 2022

The Green Bay Packers and San Francisco 49ers lock horns in the Divisional Round of the 2021 NFL Playoffs in the NFL at Lambeau Field on Saturday, with kickoff at 8:15PM EST.

Dimers' free betting picks for 49ers vs. Packers, as well as our score prediction, best odds and player props, are detailed below.

This San Francisco vs. Green Bay betting analysis is sponsored by FanDuel Sportsbook, which has a great Bet $5, Win $150 offer for new customers during this year's NFL Playoffs.

Who will win San Francisco vs. Green Bay?

Using advanced computer power and data, Dimers.com has simulated Saturday's 49ers-Packers NFL game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives the Packers a 69% chance of beating the 49ers.

MORE: Full Betting Analysis for 49ers vs. Packers

Point Spread, Moneyline and Over/Under

The Packers are -5.5 favorites against the 49ers, with -110 at Caesars Sportsbook the best odds currently available.

For the underdog 49ers (+5.5) to cover the spread, FanDuel Sportsbook has the best odds currently on offer at -106.

BetMGM currently has the best moneyline odds for the Packers at -250, which means you can risk $250 to win $100, for a total payout of $350, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the 49ers at +210, where you can bet $100 to profit $210, earning a total payout of $310, if they win.

The Over/Under for total points scored is set at 47 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best NFL odds and lines.

According to DimersBOT, the bookmakers have got it right and both the 49ers and Packers are a 50% chance of covering the spread, while the 47-point Over/Under is a 56% chance of going Over.

MORE: Super Bowl LVI Probabilities and Odds

Best Bets for 49ers vs. Packers

• Spread: 49ers +5.5 at -106 with FanDuel Sportsbook (50% probability)
• Moneyline: 49ers at +210 with FanDuel Sportsbook
• Over/Under: Over 47 at -110 with Caesars Sportsbook (56% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to help you make more informed decisions.

While the Packers are more likely to win the game, according to DimersBOT, taking the 49ers moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to being profitable in the long run.

San Francisco vs. Green Bay Score Prediction

Dimers.com's predicted final score for San Francisco vs. Green Bay at Lambeau Field this Saturday has the Packers prevailing 27-21.

Use our interactive widget below to view up-to-date Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full betting coverage of this week's 49ers-Packers matchup, including pre-game predictions, best betting picks, and live scores.

49ers vs. Packers Player Props

Who will score an anytime touchdown in 49ers vs. Packers? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the 49ers and Packers, as well as projected player stats.

And you know what, we provide this information to you for FREE to help you choose the best prop bets for Saturday's game.

According to DimersBOT, Green Bay's Davante Adams is most likely to score the first touchdown in 49ers vs. Packers.

DimersBOT gives Adams a 16.9% chance of scoring the first TD at Lambeau Field, while the Packers WR is a 60.0% chance of scoring an anytime touchdown.

First Touchdown Scorer Probabilities

San Francisco 49ers

• Deebo Samuel: 13.9% probability
• Elijah Mitchell: 10.7% probability
• George Kittle: 5.3% probability
• Brandon Aiyuk: 4.7% probability
• Jauan Jennings: 3.3% probability

Green Bay Packers

• Davante Adams: 16.9% probability
• Aaron Jones: 11.8% probability
• A.J. Dillon: 8.2% probability
• Randall Cobb: 5.4% probability
• Allen Lazard: 5.2% probability

Anytime Touchdown Scorer Probabilities

San Francisco 49ers

• Deebo Samuel: 54.0% probability
• Elijah Mitchell: 44.9% probability
• George Kittle: 28.1% probability
• Brandon Aiyuk: 23.8% probability
• Jauan Jennings: 17.6% probability

Green Bay Packers

• Davante Adams: 60.0% probability
• Aaron Jones: 46.9% probability
• A.J. Dillon: 36.1% probability
• Allen Lazard: 25.4% probability
• Randall Cobb: 25.0% probability

Projected Box Score

Of the starting quarterbacks, the 49ers' Jimmy Garoppolo is projected to have a big game with 263 passing yards and 1.2 passing touchdowns. The Packers' Aaron Rodgers is expected to throw for a whopping 271 yards and 2.0 TDs.

49ers Starting QB

• Jimmy Garoppolo: 263 Passing Yards, 1.2 Passing TDs

Packers Starting QB

• Aaron Rodgers: 271 Passing Yards, 2.0 Passing TDs

49ers Rushing

• Elijah Mitchell: 81 Rushing Yards, 0.4 TDs
• Deebo Samuel: 41 Rushing Yards, 0.3 TDs
• Jimmy Garoppolo: 6 Rushing Yards, 0.1 TDs

Packers Rushing

• A.J. Dillon: 56 Rushing Yards, 0.3 TDs
• Aaron Jones: 52 Rushing Yards, 0.4 TDs
• Aaron Rodgers: 12 Rushing Yards, 0.1 TDs

49ers Receiving

• Deebo Samuel: 85 Receiving Yards, 0.4 TDs
• George Kittle: 63 Receiving Yards, 0.3 TDs
• Brandon Aiyuk: 53 Receiving Yards, 0.2 TDs
• Jauan Jennings: 27 Receiving Yards, 0.2 TDs
• Elijah Mitchell: 14 Receiving Yards, 0.1 TDs

Packers Receiving

• Davante Adams: 92 Receiving Yards, 0.9 TDs
• Randall Cobb: 48 Receiving Yards, 0.3 TDs
• Allen Lazard: 41 Receiving Yards, 0.3 TDs
• Aaron Jones: 24 Receiving Yards, 0.2 TDs
• Josiah Deguara: 20 Receiving Yards, 0.2 TDs

Remember, DimersBOT updates often, so refresh this page for the latest betting insights ahead of 49ers vs. Packers on Saturday January 22, 2022.

Get 30/1 Odds on 49ers or Packers to Win

FanDuel Sportsbook has come to the party for the NFL Playoffs with 30/1 odds on either the 49ers or Packers to win on Saturday.

All you need to do is sign up with FanDuel Sportsbook using this exclusive link, make a first deposit of $10+, and place – as your first real-money wager – a $5 bet on either the 49ers or Packers to win at Lambeau Field.

If your team wins, you get $150 in cash money! Small risk, big reward!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

49ers vs. Packers 2022 Game Info

When do the Packers play the 49ers?

• Date: Saturday January 22, 2022
• Time: 8:15PM EST / 5:15PM PST
• Venue: Lambeau Field

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What NFL games are on today?

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Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!