2025 MLB All-Star Game Betting Preview: Odds, Lineups, and Key Trends

The 2025 MLB All-Star Game has arrived, and all eyes are on Truist Park in Atlanta, Georgia, as the sport’s biggest names take the field for this year’s Midsummer Classic.

Most bettors are eager for the regular season games to resume as the exhibition events don't always present the most profitable MLB Betting opportunities, even with superstars and awards favorites like Shohei Ohtani, Tarik Skubal and Paul Skenes under the bright lights.

This year’s MLB All-Star Game betting odds have the NL listed as slight favorites, but recent trends suggest value on the AL. Whether you're placing MLB All Star bets or just tuning in for the show, here’s everything you need to know—including updated odds, lineups, and the best trends from the last decade of All-Star action.

MLB All-Star Game 2025: Time, Location & Betting Odds

• Date: Tuesday, July 15, 2025

• Time: 8:00 PM ET

• Location: Truist Park – Atlanta, GA

• TV Broadcast: FOX

• MLB All Star Game Odds:

  • National League: -116

  • American League: -102

• Game Total (Over/Under): 7 Runs

• Starting Pitchers:

  • AL: Tarik Skubal (Detroit Tigers)

  • NL: Paul Skenes (Pittsburgh Pirates)

The 95th MLB All-Star Game marks the first time the event returns to Atlanta since Truist Park opened in 2017. Despite the National League being slight favorites in the MLB All Star betting markets, history overwhelmingly favors the AL.

RELATED: Dimers Interns Pick Winner of the Home Run Derby

MLB All-Star Game Starting Lineups

American League Starters

• C: Cal Raleigh (Mariners)

• 1B: Vladimir Guerrero Jr. (Blue Jays)

• 2B: Gleyber Torres (Tigers)

• 3B: Junior Caminero (Rays)

• SS: Jacob Wilson (Athletics)

• OF: Aaron Judge (Yankees)

• OF: Riley Greene (Tigers)

• OF: Javier Báez (Tigers)

• DH: Ryan O’Hearn (Orioles)

• SP: Tarik Skubal (Tigers)

Can Cal Raleigh become the first HR Derby winner to homer in the All-Star Game in over a decade?

National League Starters

• C: Will Smith (Dodgers)

• 1B: Freddie Freeman (Dodgers)

• 2B: Ketel Marte (Diamondbacks)

• 3B: Manny Machado (Padres)

• SS: Francisco Lindor (Mets)

• OF: Ronald Acuña Jr. (Braves)

• OF: Pete Crow-Armstrong (Cubs)

• OF: Kyle Tucker (Cubs)

• DH: Shohei Ohtani (Dodgers)

• SP: Paul Skenes (Pirates)

With superstars like Aaron Judge, Shohei Ohtani, and Ronald Acuña Jr. taking the field alongside exciting first-time All-Stars like Pete Crow-Armstrong and Jacob Wilson, this year’s rosters offer a thrilling blend of talent for fans and bettors alike.

MLB All-Star Game Trends: Key Stats for Bettors

If you're evaluating MLB All-Star Game bets or looking for angles in the betting market, these historical trends from the past 10 editions (2014–2024, skipping 2020 as the game was canceled due to the COVID-19 pandemic) could offer serious insight:

All-Star Game Winner

• Only recent NL win came in 2023

• Despite being slight underdogs (-102) in 2025, the AL has all the momentum.

Betting angle: Over the past decade (excluding the canceled 2020 game), the American League has won 9 of the last 10 MLB All-Star Games, establishing a historic level of dominance over the National League. The AL’s consistency in the Midsummer Classic, including an eight-game winning streak from 2014 to 2022, makes them a compelling option in the betting market, especially at their near-even money odds.

Over or Under the Game Total?

• Over/Under record: 4-4-2 over the last 10 going based on this year's total of 7

Betting angle: Those looking for an edge in the game total by looking at trends will find little help. The O/U is practically a perfect split over the past 10 editions, with 4 overs, 4 unders and 2 pushes landing on 7 runs. However, over the past five, there has been just one game hitting the over, making the under look like the sager play with the pitching pedigree and possibility of a push.

YRFI or NRFI?

• NRFI has hit in 6 of the last 10 games

Betting angle: If you are looking at the Under but don't like the trend, there's a bet within the bet that looks far more appealing for those banking on a lower-scoring outing. Not only does the first inning lean towards Under 0.5 runs scored with 6 our of 10 since 2014, but the NRFI is a on a 6-1 run, with 2022 the lone over in that span. It makes sense - we're seeing the top aces start and knowing they'll only pitch 1 or 2 innings at max, they're throwing gas. The books are aligned, with -170 for a NRFI at bet365.

Starting Pitchers Are In and Out

• Just 11 total pitchers have thrown more than 1.0 innings since 2014

Betting angle: Don’t expect pitchers to rack up the stats in their limited work. With a roster full of All-Star hurlers, most "starters" don't see more than 1 inning, with just 10 total pitchers throwing more than 3 outs since 2014. Of those, just Max Scherzer (2018), Chris Sale (2017) Dallas Keuchel (2015) and Sack Greinke (2015) were the game's opening starter, each throwing 2 innings. Both Tarik Skubal and Paul Skenes have their Strikeouts line set at O/U 1.5 and only Justin Verlander (2) has struck out multiple batters as the starter since 2019. Expect the deep bullpens to do the bulk work.

HR Derby Winner Also Wins All-Star Game?

• Only 2 players in the past decade won the HR Derby and also starred in the game:

  • Yoenis Céspedes (2014)

  • Aaron Judge (2017)

Betting angle: The Home Run Derby winner has rarely carried that momentum into the All-Star Game itself. In the past decade, only two Derby champions - Yoenis Céspedes in 2014  Aaron Judge in 2017 were on the winning All-Star team. Don't expect them to carry over their Monday night success either - HR derby winners (and participants) rarely go yard in the All-Star game - only Alex Bregman as a participant in 2018 (since 2014).

Extras?

• Extra innings occurred in 2017 and 2018, both 10-inning games.

Betting angle: A prop on extra innings has longshot appeal but low historical hit rate. While extra innings are rare, they have occurred twice in the last 10 games, specifically in 2017 and 2018, both of which went to 10 innings. The majority of recent games have finished in regulation, but props on extra innings may offer sneaky value if you’re looking for a longshot wager, currently priced at +600 on DraftKings for a tiebreaker a 3-player HR Derby swing-off.

Final Thoughts: Best Bets for MLB All-Star Game 2025

The MLB All-Star Game is often more about showmanship than strategy—but the recent history paints a clear betting picture favoring the American League and a lower-scoring game

Whether you're betting on the moneyline, props, or just tuning in, the 2025 MLB All-Star Game promises another chapter in this storied series—with stars shining and surprises sure to follow under the lights in Atlanta.

Responsible Gambling

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