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White Sox vs. Guardians Prediction, Picks and Odds

Our detailed prediction and analysis for the White Sox vs. Guardians MLB game on September 14, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
White Sox
2
3
Sep 14, 5:40PM Progressive Field
Guardians
Sep 14, 5:40PM Progressive Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
White Sox
0 0 0 1 1 0 0 0 0 2 5 0
Guardians
0 0 0 2 0 0 1 0 X 3 6 0
Live Probabilities
Moneyline
Over / Under
Run Line
White Sox CWS
Win %
0%
100%
Guardians CLE
Win Probability
Last At Bat
Outs
Andrew Benintendi grounds out to second base, Brayan Rocchio to CJ Kayfus.
Quick Box Score
Hitting
Pitching
White Sox Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 M. Tauchman RF400000000.000
2 K. Teel C40100020.250.500
3 L. Sosa 1B41100010.250.500
4 C. Montgomery SS300001300.250
5 M. Vargas 3B40210010.51.250
6 A. Benintendi DH400000100.000
7 W. Robertson LF300000100.000
8 C. Meidroth 2B31111010.3331.666
9 D. Fletcher CF300000100.000
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF310001000.250
2 A. Martínez CF20100010.51.500
3 J. Ramírez DH31100120.3330.833
4 J. Noel RF000000000.000
5 B. Naylor C31231100.6672.750
6 G. Arias SS400000100.000
7 D. Schneemann 3B30100010.3330.666
8 C. Kayfus 1B30100000.3330.666
9 B. Rocchio 2B200001000.333

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White Sox vs. Guardians: Detailed Breakdown

Matchup Overview

  • Teams: White Sox vs. Guardians
  • Date: Sunday, September 14, 2025
  • Time: 1:40 PM ET
  • Venue: Progressive Field

Current Betting Odds

  • Spread: Guardians favored at -1.5
  • Total (Over/Under): 7
  • Moneyline Odds: White Sox +140, Guardians -155

Dimers' Win Probabilities

  • White Sox: 42%
  • Guardians: 58%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the White Sox a win probability of 42%, while the Guardians have a win probability of 58%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Guardians are more likely to beat the White Sox in the MLB game at Progressive Field on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our White Sox vs. Guardians predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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