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Eastern Michigan vs. Buffalo Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Eastern Michigan vs. Buffalo NCAAF game on October 4, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Eastern Michigan
Predicted score
22
:
27
Oct 4, 7:30PM UB Stadium
Buffalo
Oct 4, 7:30PM UB Stadium
Game PredictionsPre-Game
Dimers Pro Best Bets
Pre-Game Probabilities Last Updated: 7:44PM, Sep 29
Spread
Over / Under
Moneyline
Eastern Michigan
Eastern Michigan +9.5
Spread
60%
40%
Buffalo
Eastern Michigan EMU
Eastern Michigan +9.5
Spread
60%
40%
Buffalo BUFF

Game Prediction Article

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Eastern Michigan vs. Buffalo: Detailed Breakdown

Matchup Overview

  • Teams: Eastern Michigan vs. Buffalo
  • Date: Saturday, October 4, 2025
  • Time: 3:30 PM ET
  • Venue: UB Stadium

Current Betting Odds

  • Spread: Buffalo favored at -9.5
  • Total (Over/Under): 49.5
  • Moneyline Odds: Eastern Michigan +280, Buffalo -315

Dimers' Win Probabilities

  • Eastern Michigan: 34%
  • Buffalo: 66%

Dimers.com's predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Eastern Michigan 22-27 Buffalo.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Eastern Michigan a win probability of 34%, while Buffalo has a win probability of 66%.

Summary

According to our analysis, Buffalo is more likely to beat Eastern Michigan in CFB action at UB Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Eastern Michigan vs. Buffalo predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.

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